NCTS (South)





SPEAKER Prof. Jianping Lu - Department of Physics and Astronomy, Curriculum in Applied Science and Engineering, Biomedical Research Imaging Center, University of North Carolina at Chapel Hill

TITLENanotechnology X-Ray For Medical Imaging And Radiotherapy

ABSTRACTIn this talk I will give an introductory review of carbon nanotubes based field emission x-ray (CNT X-ray) technology and its application in medical imaging and radiotherapy. CNT x-ray utilizes the excellent field emission properties of CNT for electron source in x-ray tube. This enables a new generation of pulse x-ray sources which have superior temporal properties and can generate multi x-ray beams from 1-D or 2-D spatial distributed focus points.[1-4] The application of CNT x-ray includes dynamical micro-CT scanner for small animal imaging with high spatial and temporal resolution,[5-7]; stationary digital breast tomosynthesis scanner for better detection and diagnostic of breast cancer [8,9]; and table top microbeam radiotherapy system for brain cancer.


1.X-ray generating mechanism using electron field emission cathode, O. Zhou and J. Lu, US Patent 6,553,096, US Patent 6,850,595.
2.Large-area individually addressable multi-beam x-ray system and method of forming same, O. Zhou, J. Lu, Q. Qiu, US Patent 6,876724.
3.X-ray imaging systems and methods using temporal digital signal processing for reduced noise and for obtaining multiple images simultaneously, Jianping Lu, Otto Zhou, Jian Zhang, US Patent 7,245,692.
4.Systems and methods for x-ray imaging and scanning of objects, Jianping Lu, Otto Zhou, Qi Qiu, US Patent 7,486,772.
5.A stationary scanning X-ay imaging system based on carbon nanotube field emitters J. Zhang, G. Yang, R. Rajaram, E. Guan, Y. Lee, D. LaLush, S. Chang, J.P. Lu, O. Zhou,
Medical Physics 33 (6): 2159, JUN 2006.
6.A dynamic micro-CT scanner based on a carbon nanotube field emission x-ray source
G Cao, Y Z Lee, R Peng, Z Liu, R Rajaram, X Calderon-Colon3, L An, P Wang, T Phan, S Sultana, D Lalush, J Lu and O Zhou, Phys. Med. Biol. 54, 2323-2340 (2009).
7.Prospective-gated cardiac micro-CT imaging of free-breathing mice using carbon nanotube field emission x-ray, Guohua Cao, Laurel M. Burk, Yueh Z. Lee, Xiomara Calderon-Colon, Shabana Sultana, Jianping Lu, and Otto Zhou, Med. Phys. 37, 37, 5306-12 (2010).
8.Design and characterization of a spatially distributed multibeam field emission x-ray source for stationary digital breast tomosynthesis, X. Qian, R Rajaram, X Calderon-Colon, G. Yang, T Phan, , D. Lalush, Jianping Lu, Otto Zhou, Med. Phys. Volume 36, Issue 10, pp. 4389-4399 (2009).
9.Distributed source x-ray tube technology for tomosynthesis imaging, F. Sprenger, X. Calderon-Colon, Y. Cheng, K. Englestad, J. Lu, J. Maltz, A. Paidi, X. Qian, D. Spronk, S. Sultana, G. Yang, and O. Zhou, Proc. SPIE 7622, 76225M (2010).